Table 1.
Clinical, laboratory and electroencephalographic features of cases classified as atypical/rapidly progressive neurodegenerative dementia
| a/rpAD | a/rpDLB | a/rpFTLD | |
|---|---|---|---|
| No. of subjects | 37 | 11 | 9 |
| Clinical presentation | |||
| Cognitive decline | 37/37 | 11/11 | 9/9 |
| Extrapyramidal signs | 5/37 | 11/11 | 3/9 |
| Pyramidal signs | 3/37 | 0/11 | 1/9 |
| Myoclonus | 5/37 | 3/11 | 3/9 |
| Akinetic mutism | 5/37 | 1/11 | 2/9 |
| Biomarker data | |||
| t-tau > 1100 pg/ml | 19/37 | 5/10 | 2/9 |
| Positive 14-3-3 | 4/37 | 3/10 | 1/9 |
| EEG PSWC | 5/37 | 4/11 | 1/9 |
Abbreviations: AD Alzheimer’s disease, a/rp Atypical/rapidly progressive, DLB Dementia with Lewy bodies, EEG Electroencephalographic, FTLD Frontotemporal lobar degeneration, PSWC Periodic sharp wave complexes, t-tau Total tau protein