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Time to maximal HupA effect. (A) Comparison of sham and TBI groups in terms of time to maximal HupA effect demonstrated as Tukey box plot. Time to maximal HupA effect was delayed in the TBI group (p = 0.03). (B) Polynomial best fit curves with 95% confidence intervals and the vertices for sham and TBI groups shown. Round and squared dots represent the vertices of sham (n = 6) and TBI (N = 6) groups, respectively. HupA, huperzine A; TBI, traumatic brain injury.
