Table 1. SMC complexes, adaptor proteins, and associated histone modifications.
| Complex | Organism | DNA site | Sequence recognizer | Epigenetic marks |
|---|---|---|---|---|
| SMC | Bacillus subtilis | parS | ParB (31,32) | NA |
| Condensin | Yeast/mouse/human | B box | TFIIIC (22,37) | H3K4me3 (22) |
| H4K20me1 (44) | ||||
| Flies | Mrg15 (52,53) | acetylated lysines on histone tails | ||
| Mammals/flies | pRB (54) | |||
| Mammals | Brd4 (51) | methylated lysines on histone tails | ||
| Cohesin | Mouse/human | CCCTC | CTCF (27,28) | unknown |
| Dosage compensation | C. elegans | rex | unknown | H4K20me1 (45,46) |
Abbreviations: NA, not applicable; SMC, structural maintenance of chromosome.