Fig 6. Cytotoxic effects of highly oxidized LDL on EA.hy926 cells in the presence of increasing medium concentrations of EP.

nLDL (1.5 mg/mL) was oxidized by addition of 10 μmol/L CuCl₂ in the absence of EP in order to obtain the highly cytotoxic form of oxLDL. EP added to the culture medium concentration-dependently attenuated the cytotoxic effect of this oxLDL on EA.hy926 cells, reflected in increased viability (A) and decreased levels of superoxide radical anion formation (B). Data represent mean ± SD (n = 6 for metabolic activity, n = 4 for superoxide levels), * p < 0.05, *** p < 0.001.