Table 5. An admission BUN concentration above 28mg/dL is associated with mortality after correction for several cofounders in a multivariate analysis.
multivariate model 1 | ||||||
univariate | multivariate | |||||
HR | 95%CI | p-value | HR | 95%CI | p-value | |
BUN >28 mg/dL | 3.74 | 3.29–4.25 | <0.001 | 1.89 | 1.59–2.26 | <0.001 |
APACHE2 | 1.07 | 1.07–1.08 | <0.001 | 1.07 | 1.06–1.08 | <0.001 |
multivariate model 2 | ||||||
univariate | multivariate | |||||
HR | 95%CI | p-value | HR | 95%CI | p-value | |
BUN >28 mg/dL | 3.74 | 3.29–4.25 | <0.001 | 1.85 | 1.55–2.21 | <0.001 |
SAPS2 | 1.04 | 1.03–1.04 | <0.001 | 1.03 | 1.03–1.04 | <0.001 |
multivariate model 3 | ||||||
univariate | multivariate | |||||
HR | 95%CI | p-value | HR | 95%CI | p-value | |
BUN >28 mg/dl | 3.74 | 3.29–4.25 | <0.001 | 3.34 | 2.89–3.86 | <0.001 |
creatinine (mg/dL) | 1.001 | 1.001–1.001 | <0.001 | 1.02 | 0.98–1.05 | 0.44 |
age (y) | 1.02 | 1.02–1.03 | <0.001 | 1.02 | 1.01–1.02 | <0.001 |
sex (m/w) | 0.97 | 0.86–1.08 | 0.55 | 0.9 | 0.79–1.03 | 0.9 |
lactate (mmol/L) | 1.06 | 1.06–1.07 | <0.001 | 1.07 | 1.06–1.07 | <0.001 |