Skip to main content
. Author manuscript; available in PMC: 2018 Jan 25.
Published in final edited form as: Aliment Pharmacol Ther. 2016 Aug 24;44(8):817–835. doi: 10.1111/apt.13780

Table 4.

Genetic association studies increasing risk for pouchitis

Genes SNP (rs#) Population N Reference
IL-1RN*2 N/A Northern European Controls N = 82
Pouchitis N = 29		 135
IL-1RN*1
TNF*1 		N/A
N/A		 USA Controls N = 52
≤2 Pouchitis Episodes/Year N = 11
>2 Pouchitis Episodes/Year N = 39		 136
ATG16L1
U6
JAK2 		rs2241880
rs6927210
rs7849191		 USA Controls N = 63
Mild Pouchitis N = 41		 132
TNFSF15
NOD2
S100Z 		rs7869487
rs2066844
rs7712957		 USA Controls N = 63
Severe Pouchitis N = 12		 132
TLR9
CD14 		rs574383, rs2569190 Italian Controls N = 224
Pouchitis N = 78		 137
NOD2 rs2066844
 USA Controls N = 37
Mild Pouchitis N = 33		 138
NOD2
 rs2066847 USA Controls N = 37
Severe Pouchitis N = 9		 138
NOD2 rs2066847 USA and Canada Controls N = 487
Chronic Pouchitis N = 118		 129