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. 2017 Nov;14(4):387–395. doi: 10.20892/j.issn.2095-3941.2017.0050

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MiRNA binding alterations due to SNP rs4245739. (A) Distribution of SNPs located at the 3’UTR and 5’UTR per 100,000 bases in comparison to coding regions (NS) in the human genome (left panel). Schematic description of how SNP located at the 3’UTR might influence binding sites of miRNA (right panel). (B) Schematic representation of SNP rs4245739, which is located at the 3’UTR of the MDM4 gene. (C) Potential binding alterations of several miRNAs due to rs4245739 that affect not only miR-191 but also 16 additional miRNAs.