2.

Association of UCPs with patient and disease characteristics

	UCP1				UCP3
	No/weak	Strong	P-value		No/weak	Strong	P-value
* Squamous vs. other. ** Large cell vs. other. *** In squamous and adenocarcinomas
Histology
Adenocarcinoma	16	6	0.05*		17	5	0.08**
Large cell	11	7			10	8
Squamous cell	28	20			44	14
Stage
I	15	21	0.93		34	12	0.87
II	13	9			15	7
III	17	13			22	8
Grade***
1–2	26	26	0.22		42	10	0.19
3	18	10			19	9
Necrosis
No	46	38	0.57		57	27	0.009
Yes	9	5			14	0
Gender
F	11	1	0.008		8	4	0.63
M	44	42			63	23
Age (years)
< 61	10	17	0.01		20	7	0.82
> 60	45	26			51	20