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. 2017 Sep 5;14(11):1580–1591. doi: 10.1080/15476286.2017.1338232

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© 2017 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 5. — Co-localization of FMRP and ADAR2 in hippocampal sections by electron microscopy. (A-C) Two representative electronic micrographics of a double-immunogold for FMRP (labeled by 10 nm gold particles) and ADAR2 (labeled by 15 nm gold particles) performed on hippocampal ultra-thin sections of adult male mice. The red boxes highlight the co-localization of FMRP and ADAR2 proteins inside the nucleus (Nu). Magnification: 20000 x (B) 30000 x magnification of black box showed in panel A. Red arrows show FMRP/ADAR2 co-localization. (D) 30000 x magnification of black box in panel C. Red arrows show FMRP/ADAR2 co-localization. Nu: Nucleus; Cyt: Citoplasm.