Figure 6.
Detection of endogenous ADAR2 and FMRP interaction by Proximity Ligation Assay (PLA) in mouse primary cortical neuron cultures. (A-B) PLA dots for ADAR2 and FMRP show manly a nuclear localization. (C) PLA dots for FMRP and FXR1P interaction are in the cytoplasm; (D) Without-primary-ADAR2 antibody processed samples do not show any dot in PLA experiment. Scale bars 5µm.