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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Anesth Analg. 2017 Nov;125(5):1682–1703. doi: 10.1213/ANE.0000000000002426

Table 7.

Radicular Pain – Effective Medications based on Included Studies

Radicular Pain – Effective Medications

FDA On-Label Off-Label
Topical (non-local anesthetic)
 None None

Amine Reuptake Inhibitors (ARI)
 None Duloxetine, Milnacipran, Amitrptyline

Membrane Stabilizers
 None None

ARI/Opioid
 None None

Local Anesthetics
 None None

NMDA Antagonists
 None None

Miscellaneous
 None Indomethacin

FDA: Food and Drug Administration; ARI: amine reuptake inhibitor; NMDA: N-methyl-D-aspartate