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. 2018 Jan 22;128(2):846–860. doi: 10.1172/JCI96186

Figure 1. Osteoclastic bone resorption in SMTS enthesopathy mice.

Figure 1

(A) μCT images of the PCT (sagittal view). Red arrowhead indicates altered morphology of the PCT. Red asterisk indicates bone marrow cavities. Scale bar: 500 μm. (B) Quantitative analysis of BV/TV, Tb.Th, Tb.N, Tb.Sp, and Tb.Pf in PCT determined by μCT analysis. (C) TRAP staining (magenta) in mouse PCT bone marrow. Scale bar: 200 μm. Red asterisks indicate bone marrow cavities. (D) Quantitative analysis of TRAP+ OCS/BS. (E) Quantitative analysis of active TGF-β1 in serum by ELISA. D0, prior to SMTS surgery; Sham, sham surgery; W1, 1 week after SMTS surgery. Data shown as mean ± SEM. n = 10. *P < 0.05 compared with the sham group.