Figure	Sub panel	Test	Biological Replicates	P value
4B	4C-seq	Student’s T-Test	3	0.011
4B	ChIP-qPCR	Student’s T-Test	3	0.0066
4B	RT-qPCR	Student’s T-Test	6	< 0.0001
4C	4C-seq	Student’s T-Test	3	0.0013
4C	ChIP-qPCR	Student’s T-Test	3	0.0048
4C	RT-qPCR	Student’s T-Test	6	0.0394
6B	Welch	Two Sample T-Test	3	< 2.2e-16
6D	HiChIP	Student’s T-Test	3	0.0162
6D	RNA-seq	Wald	2	7.22E-13
6E	HiChIP	Student’s T-Test	3	0.0446
6E	RNA-seq	Wald	2	1.25E-58
7D	4c-seq	Student’s T-Test	3	0.004717003
7D	RT-qPCR	Student’s T-Test	6	< 0.0001
S6D	Raf1 Wald	2		1.63E-53
S6D	Etv4 Wald	2		2.88E-34

^*note that the Student’s t test was conducted using GraphPad Prism which sets a lower limit at 0.0001, the Welch Two Sample t test was conducted using R which sets a lower limit at 2.2e-16, Wald test was conducted using deseq2 in R which does not have a lower limit on the p value.