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Ultraviolet radiation (UVR)-induced cyclobutane pyrimidine dimers (CPD) in skin from a randomized, controlled study of 12 weeks of supplementation with green tea catechins and vitamin C versus placebo. Representative immunohistochemistry and quantification of CPD in UVR-exposed (3 × minimal erythema dose; MED) and unexposed skin at baseline and postsupplementation. Active n = 20 subjects, placebo n = 24 subjects. Scale bar = 50 μm.
