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. 2017 Dec 2;55(2):560–567. doi: 10.1007/s13197-017-2965-1

Table 2.

Effects of Thymus pannonicus deodorised water extract (DWE) (5% m/V, 2 mL/kg b.w.) on the activities of antioxidant enzymes, reduced glutathione (GSH) level and intensity of lipid peroxidation (LPx) in EAC cells

Group XOD (µmol mL−1) CAT (µmol mL−1) Px (µmol mL−1) GR (µmol mL−1) GSHPx (µmol mL−1) GSH (nmol mg−1) LPx (nmol MDA mg−1)
Males
 CTRL 0.123 ± 0.011 0.445 ± 0.012 0.279 ± 0.001 1.38 ± 0.01 0.772 ± 0.009 1.50 ± 0.02 0.029 ± 0.001
 G1 3.22 ± 0.14* 0.458 ± 0.029 0.922 ± 0.11* 3.45 ± 0.21* 4.82 ± 0.36* 0.312 ± 0.11* 0.91 ± 0.11*
 G2 1.56 ± 0.18* 0.311 ± 0.021 0.627 ± 0.065 2.78 ± 0.17 5.11 ± 0.34 0.587 ± 0.12* 0.078 ± 0.053
 G3 0.538 ± 0.12 0.284 ± 0.10 0.302 ± 0.078 2.07 ± 0.26 3.67 ± 0.25 0.945 ± 0.11* 0.074 ± 0.061
Females
 CTRL 0.152 ± 0.013 0.512 ± 0.023 0.328 ± 0.001 2.24 ± 0.05 0.783 ± 0.011 1.63 ± 0.01 0.031 ± 0.001
 G1 4.15 ± 0.15** 0.247 ± 0.11** 0.912 ± 0.13** 3.78 ± 0.34 3.87 ± 0.64** 0.248 ± 0.12** 0.24 ± 0.09**
 G2 1.69 ± 0.17** 0.287 ± 0.12 0.547 ± 0.078 2.92 ± 0.18 3.12 ± 0.57 0.694 ± 0.09** 0.064 ± 0.037
 G3 0.684 ± 0.13 0.413 ± 0.069 0.327 ± 0.091 2.07 ± 0.31 2.08 ± 0.34 1.26 ± 0.05 0.040 ± 0.012

Values are expressed as mean ± SD of six mice at p < 0.05. Activities of xanthine oxidase (XOD), catalase (CAT), peroxidase (Px), glutathione reductase (GR) and glutathione peroxidase (GSHPx) are expressed in µmol/mL EAC cells. The content of glutathione (GSH) and intensity of lipid peroxidation (LPx) are expressed in nmol/mg of protein content in EAC cells

CTRL, untreated control group; G1, G2 and G3, animals pretreated, treated at the time of implantation of EAC cells, or posttreated with DWE, respectively

* Significantly different from the male control group at p < 0.05. ** Significantly different from the female control group at p < 0.05