Table 2.
Group | XOD (µmol mL−1) | CAT (µmol mL−1) | Px (µmol mL−1) | GR (µmol mL−1) | GSHPx (µmol mL−1) | GSH (nmol mg−1) | LPx (nmol MDA mg−1) |
---|---|---|---|---|---|---|---|
Males | |||||||
CTRL | 0.123 ± 0.011 | 0.445 ± 0.012 | 0.279 ± 0.001 | 1.38 ± 0.01 | 0.772 ± 0.009 | 1.50 ± 0.02 | 0.029 ± 0.001 |
G1 | 3.22 ± 0.14* | 0.458 ± 0.029 | 0.922 ± 0.11* | 3.45 ± 0.21* | 4.82 ± 0.36* | 0.312 ± 0.11* | 0.91 ± 0.11* |
G2 | 1.56 ± 0.18* | 0.311 ± 0.021 | 0.627 ± 0.065 | 2.78 ± 0.17 | 5.11 ± 0.34 | 0.587 ± 0.12* | 0.078 ± 0.053 |
G3 | 0.538 ± 0.12 | 0.284 ± 0.10 | 0.302 ± 0.078 | 2.07 ± 0.26 | 3.67 ± 0.25 | 0.945 ± 0.11* | 0.074 ± 0.061 |
Females | |||||||
CTRL | 0.152 ± 0.013 | 0.512 ± 0.023 | 0.328 ± 0.001 | 2.24 ± 0.05 | 0.783 ± 0.011 | 1.63 ± 0.01 | 0.031 ± 0.001 |
G1 | 4.15 ± 0.15** | 0.247 ± 0.11** | 0.912 ± 0.13** | 3.78 ± 0.34 | 3.87 ± 0.64** | 0.248 ± 0.12** | 0.24 ± 0.09** |
G2 | 1.69 ± 0.17** | 0.287 ± 0.12 | 0.547 ± 0.078 | 2.92 ± 0.18 | 3.12 ± 0.57 | 0.694 ± 0.09** | 0.064 ± 0.037 |
G3 | 0.684 ± 0.13 | 0.413 ± 0.069 | 0.327 ± 0.091 | 2.07 ± 0.31 | 2.08 ± 0.34 | 1.26 ± 0.05 | 0.040 ± 0.012 |
Values are expressed as mean ± SD of six mice at p < 0.05. Activities of xanthine oxidase (XOD), catalase (CAT), peroxidase (Px), glutathione reductase (GR) and glutathione peroxidase (GSHPx) are expressed in µmol/mL EAC cells. The content of glutathione (GSH) and intensity of lipid peroxidation (LPx) are expressed in nmol/mg of protein content in EAC cells
CTRL, untreated control group; G1, G2 and G3, animals pretreated, treated at the time of implantation of EAC cells, or posttreated with DWE, respectively
* Significantly different from the male control group at p < 0.05. ** Significantly different from the female control group at p < 0.05