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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Dev Biol. 2017 Dec 20;434(1):186–195. doi: 10.1016/j.ydbio.2017.12.013

Fig. 5.

Fig. 5

Whole-mount in situ hybridization of PITX1-dependent genes in wide-type and Pitx1−/− mouse embryos. A–F) The expression pattern of limb patterning genes (Alx3, HoxD10 and Bmp4). G–L) The expression pattern of genes related to cartilage development (Sox9, Col2a1 and Pax9). M–R) The expression pattern of genes related to muscle development (Mef2c, MyoD and Myogenin). Red arrowheads point to regions with increased expression while blue ones point to regions with decreased expression in Pitx1−/− mouse embryos. All images were taken at the same magnification. Scale bar = 500 μm.