Figure 4.

CbpS436A Modulates Post-stroke Functional Recovery without Altering Stroke Volume

(A and B) Images (A) and quantification (B) of infarct volumes at 3 and 14 days post stroke from WT and CbpS436A-KI mice. Scale bars, 50 μm (n = 6/group for 3 days; n = 9/group for 14 days).

(C) The percentage of forelimb error step at 7 and 14 days post stroke in WT and CbpS436A mice, analyzed by two-way ANOVA (Time × Genotype with forelimbs F(6,168) = 0.76, p = 0.7587, n = 17 for WT, n = 13 for KI), with Tukey's post hoc test, ^∗p < 0.05 compared with WT, n = 13–17/group.

(D) The ipsilateral preference in the cylinder test at 7 and 14 days post stroke in WT and CbpS436A-KI mice, analyzed by two-way ANOVA (Time × Genotype F(2,42) = 2.395, p = 0.1035, n = 17 for WT, n = 13 for KI) with Tukey's post hoc test, ^∗p < 0.05 compared with WT, n = 13–17/group.

Error bars in this figure represent the SEM.