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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Am J Obstet Gynecol. 2017 Nov 1;218(1):136.e1–136.e10. doi: 10.1016/j.ajog.2017.10.040

Figure 3. High glucose-increased miR-27a suppresses Nrf2 expression.

Figure 3

A. miR-27a levels in C17.2 cells treated with normal (5 mM) or high (25 mM) glucose combined with miR-27a inhibitor for 48 h. B. Nrf2 mRNA levels in C17.2 cells treated with normal (5 mM) or high (25 mM) glucose, combined with miR-27a inhibitor for 48 h. C. Nrf2 protein levels in C17.2 cells treated with normal (5 mM) or high (25 mM) glucose, combined with miR-27a inhibitor for 48 h. D. miR-27a levels in C17.2 cells transfected with miR-27a mimic for 48 h. E. Nrf2 mRNA levels in C17.2 cells transfected with miR-27a mimic for 48 h. F. Nrf2 protein levels in C17.2 cells transfected with miR-27a mimic for 48 h. Experiments were repeated three times. Bar graphs for protein levels show quantitative data from three independent experiments. * indicates a significant difference (P < 0.05) compared with other groups. # indicates significant difference (P < 0.05) compared to control group.