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Cmax and AUC168➔192 of fenofibric acid at steady state from simulated data using final MBPK model and results of ANOVA
| Mean ± S.E. | Group 1 | Group 2 | Group 3 |
|---|---|---|---|
| Food type | Fasting condition | Normal meal | High fat meal |
| Cmax (μ g/mL) | 3.17 ± 0.07 | 4.33 ± 0.10* | 4.83 ± 0.11*† |
| AUC168➔192 (μ g∙hr./mL) | 319.14 ± 7.48 | 432.90 ± 10.33* | 483.63 ± 11.55*† |
*: p < 0.01 vs the Group 1; †: p < 0.01 vs the Group 2
