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. 2017 Aug 25;11(6):587–603. doi: 10.1080/19336950.2017.1365206

Figure 4.

Figure 4.

AITC has no effect on [Ca]I and shortening in CMs obtained from TRPA1 null mice. Original traces demonstrating the lack of effect of AITC (100 μmol/L) on steady-state sarcomere length (µm; panel A) and [Ca2+]i (340/380 ratio; panel B) in an individual mouse ventricular myocyte obtained from TRPA1 null mice (TRPA1−/−). AITC was added where indicated on the figure. Exploded views of changes in sarcomere length and [Ca2+]i before and after addition of AITC are depicted in panels C-F. n = 8 cells from 4 hearts.