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Glucose-tolerance and insulin-tolerance is impaired upon shRNA-mediated SWELL1 KD in obese mice. (A) Glucose-tolerance test; (B) Insulin-tolerance test. Error Bar: Mean ± SEM. n = 10 shSCR Regular & HFD, n = 9 shSWELL1 HFD group. *p < 0.05; ***p< 0.001; ****p < 0.0001, 2-way Anova.
