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. 2017 Sep 21;11(6):517–533. doi: 10.1080/19336950.2017.1369637

Figure 3.

Figure 3.

Structures involved in inactivation within the Nav1.5 α-subunit. Structures colored in red significantly affect fast inactivation. From N-terminal to C-terminal, the intracellular end of DI S6 segment (ΔWCW window),45,47 intracellular end of DII S6 segment,45 DIII S4-S5 linker,38,39,42 DIII-DIV linker,25-33 DIV S4-S5 linker,40-42 lower half of DIV S6 segment,44,47 and C-terminus.23,48-51,53