Figure 2.
Involvement of dCT and Ser1928 in PKC regulation of α1C. Giant oocyte membrane patches were stained for α1C before and after PKC activation by PMA. Oocytes were injected with 5 ng channel RNA/oocyte. (A) Activation of PKC significantly enhanced PM expression in oocytes expressing α1CΔ1821 (n = 6), but not in oocytes coexpressing α1CΔ1821 and dCT (n = 5). (B) Activation of PKC failed to increase PM expression in oocytes expressing α1C S1928A (n = 28) as compared with control, wt α1C (n = 22).