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. 2018 Jan 16;14(1):e1005896. doi: 10.1371/journal.pcbi.1005896

Fig 5. Differences in changes in transcription factor binding in A549 cells in response to glucocorticoid exposure for the four largest DPGP clusters.

Fig 5

(A) Heatmap shows all coefficients (sorted by sum of absolute value across clusters) for predictors with non-zero coefficients as estimated by elastic net logistic regression of cluster membership for the four largest DPGP clusters. Predictors on y-axis represent log fold-change in normalized binned counts of TF binding from ethanol to dex conditions as assayed by ChIP-seq. Distance indicated in row names reflects the bin of the predictor (e.g., 1 kb = within 1 kb of TSS). (B) Boxplots show the logFC in normalized binned counts across clusters and for the group of non-DE transcripts for CREB1, (C) FOXA1, and (D) USF1.