TABLE 2.

FDG-PET data for the entire (global) CJD group and the different clinical CJD subgroups.

CJD-control analysis; inter-CJD analysis (* is added when hypometabolic brain areas corresponded to the clinical signs)
	Global	Cerebellar ataxia	Visual signs	Pyramidal signs	Myoclonus	Limb apraxia	Limb dystonia	Sensory loss	Parkinsonism	Corticobasal syndrome
orbitofrontal cortex									left>right
mesial frontal cortex						bilateral
lateral frontal cortex	left	left	left	left	left	left left	left		left	left
lateral prerolandic frontal cortex							left*			left*
frontal subcortical lobe		right	right
lateral parietal cortex					left left*	left left*	left left*			left left*
mesial parietal cortex	left>right	left>right	left	left	left>right	bilateral	left		left>right	left left
mesial temporal cortex		left
lateral posterior temporal cortex	left	left	right		left				left	left left
lateral temporal-occipital cortex							left
mesial occipital cortex						left
occipital cortex			left right≥left *			left
subcortical occipital lobe				left
anterior deep grey matter			left
pons		bilateral *
middle cerebellar peduncles		left≥right*