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. 2018 Jan 22;6:1. doi: 10.3389/fbioe.2018.00001

Figure 1.

Figure 1

Impaired endothelial tube formation and migration with microRNA (miR)-146a knockdown in vitro. (A,B) Tube formation of human umbilical vein endothelial cells (HUVECs) transfected with 30 nM scramble or anti-miR-146a oligonucleotides after 6 h of exposure to growth [20% O2, 10% fetal bovine serum (FBS)] or hypoxia serum starvation (HSS) conditions (n = 3). (C,D) Endothelial wound closure in HUVECs after 12 h of exposure to either growth [(C), n = 4] or HSS [(D), n = 4] conditions. Student’s t-test. Data are mean ± SEM.