Table 2.
12 weeks | 30 weeks | |||
---|---|---|---|---|
WT | A2A-AR | WT | A2A-AR | |
CSQ | 100 ± 11 | 100 ± 11 | 100 ± 7 | 89 ± 5 |
Gsα | 100 ± 6 | 64 ± 4∗ | 100 ± 7 | 66 ± 6∗ |
Giα | 100 ± 11 | 109 ± 10 | 100 ± 10 | 148 ± 13∗ |
JCN | 100 ± 15 | 99 ± 15 | 100 ± 9 | 109 ± 11 |
PLB | 100 ± 15 | 148 ± 23 | 100 ± 11 | 140 ± 16 |
SERCA | 100 ± 16 | 119 ± 20 | 100 ± 10 | 125 ± 11 |
TRD | 100 ± 16 | 100 ± 15 | 100 ± 6 | 120 ± 19 |
Data are given as % of expression in corresponding WT animals (n = 6 each). CSQ, calsequestrin; Gsα, α-subunit of stimulatory G protein; Giα, α-subunit of inhibitory G protein; JCN, junctin; PLB, phospholamban; SERCA, sarcoendoplasmatic Ca2+-ATP-ase; TRD, triadin. ∗p < 0.05 vs. corresponding WT.