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. 2018 Jan 22;8:993. doi: 10.3389/fphar.2017.00993

Table 1.

Mouse models utilized and their Taar1 genotypes.

Mouse model Background genotype Taar1 genotype Phenotype tested
C57BL/6J × DBA/2J F2 Mixed C57BL/6J and DBA/2J Taar1m1J/m1J, Taar1m1J/+, and Taar1+/+ MA intake
MAHDR selected line Mixed C57BL/6J and DBA/2J Taar1m1J/m1J MA intake
MALDR selected line Mixed C57BL/6J and DBA/2J Taar1m1J/+ and Taar1+/+ MA intake
BXD RI strains Mixed C57BL/6J and DBA/2J Taar1m1J/m1J and Taar1+/+ MA intake, MA-induced CTA, thermal response to MA
DBA/2J inbred strain Homozygous DBA/2J Taar1m1J/m1J MA intake, MA-induced CTA, thermal response to MA
DBA/2NCrl inbred strain Homozygous DBA/2 Taar1+/+ MA intake, MA-induced CTA
DBA/2NHsd inbred strain Homozygous DBA/2 Taar1+/+ MA intake, MA-induced CTA
DBA/2NTac inbred strain Homozygous DBA/2 Taar1+/+ MA intake, MA-induced CTA, thermal response to MA