Fig. 1.

a Bone marrow aspirate smears showed near-total replacement of normal hematopoietic components by a heterogenous population of small to medium sized blasts with round to slightly indented nuclei, condensed chromatin, inconspicuous nucleoli and scant cytoplasm. b Blasts were negative for Myeloperoxidase stain. c Bone Marrow Biopsy showing diffuse replacement with immature cells. d PAX5 nuclear positivity; of moderate intensity in one population of blasts. e Strong CD3 positivity in another population of blasts. f Down-regulated CD2 in CD3 positive blasts G) Areas with CD3 negative blasts. h–o Flowcytometric analysis of blasts showing positive expression of CD34, CD33, CD7 with heterogenous expression of CD19 (49%, moderate intensity), cytoCD79a (42.6%, moderate intensity)and cytoCD3(14%, dim to moderate)