Skip to main content
. 2018 Mar;22(2):78–89. doi: 10.22034/ibj.22.2.78

Table 2.

Characteristics of studies included in Prothrombin G20210A, FVL G1691A, and PAI-1 4G/5G polymorphisms and RPL

First author Year Case/control Cases Controls MAFs HWE


Genotype Allele Genotype Allele
Prothrombin G20210A GG AG AA G A GG AG AA G A

Bagheri[8] 2011 70/60 48 22 0 118 22 57 3 0 117 3 0.025 0.842
Kazerooni[10] 2013 60/60 52 8 0 112 8 54 6 0 114 6 0.050 0.683
Teremmahi Ardestani[21] 2013 80/80 80 0 0 160 0 80 0 0 160 0 0.00 0.683
Parand[21] 2013 90/44 88 2 0 178 2 43 1 0 87 1 0.011 0.939
Farahmand [16] 2015 330/350 316 14 0 646 14 340 10 0 690 10 0.014 0.786

FVL 1619 G/A GG AG AA G A GG AG AA G A

Bagheri[8] 2011 70/60 70 0 0 140 0 60 0 0 120 0 0.00 0.786
Kazerooni[10] 2013 60/60 43 12 5 98 22 54 4 2 112 8 0.066 0.003
Torabi[22] 2012 100/100 87 12 1 186 14 96 4 0 196 4 0.002 0.833
Teremmahi Ardestani[20] 2013 80/80 78 2 0 158 2 79 1 0 159 1 0.006 0.955
Parand[21] 2013 90/44 72 15 3 159 21 38 6 0 82 6 0.068 0.627
Farahmand[16] 2015 330/350 302 28 0 632 28 340 10 0 690 10 0.014 0.786
Arabkhazaeli[19] 2016 100/100 95 5 0 195 5 91 9 0 191 9 0.045 0.637

PAI-1 4G/5G 5G5G 5G4G 4G4G 5G 4G 5G5G 5G4G 4G4G 5G 4G

Jeddi-Tehrani[9] 2011 100/100 60 31 9 151 49 72 27 1 171 29 0.145 0.373
Aarabi[23] 2010 54/99 21 23 10 65 43 31 66 2 128 70 0.353 <0.001
Idali[12] 2012 106/100 35 53 18 123 89 72 27 1 171 29 0.145 0.373
Khosravi[24] 2013 595/100 128 208 85 464 378 72 27 1 171 29 0.145 0.373
Shakarami[25] 2015 100/100 33 50 17 116 84 45 50 5 140 60 0.300 0.056

MAFs, minor allele frequencies; HWE, Hardy-Weinberg equilibrium