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. 2018 Feb;52:28–42. doi: 10.1016/j.canep.2017.11.005

Table C3.

Estimated number of true positives, false positives, true negatives and false negatives, with associated sensitivity, specificity, positive predictive value and negative predictive values (95% confidence intervals), for the 60% early stage target given performance similar to 2013 and tumours counts as in 2013 for reporting periods of 1, 2.5 and 9 years.

Reporting period 1 year
2.5 years
9 years
Expected value (95% CI) Expected value (95% CI) Expected value (95% CI)
True positives 21 (13, 50) 23 (15, 32) 25 (16, 35)
False positives 19 (11, 28) 11 (6, 18) 5 (1, 10)
True negatives 161 (149, 172) 169 (157, 179) 175 (164, 185)
False negatives 8 (3, 14) 6 (2, 11) 4 (1, 8)
Sensitivity 0.73 (0.56, 0.89) 0.80 (0.64, 0.93) 0.88 (0.73, 0.97)
Specificity 0.89 (0.85, 0.94) 0.94 (0.90, 0.97) 0.97 (0.94, 0.99)
Positive predictive value 0.52 (0.37, 0.68) 0.67 (0.50, 0.82) 0.83 (0.68, 0.95)
Negative predictive value 0.95 (0.92, 0.98) 0.97 (0.94, 0.99) 0.68 (0.96, 0.99)