TABLE 2.
Comparison of phenotypic DST and WGS results for the three MDR patients
| Patient no. | RIFa |
INH |
PZA |
EMB |
STR |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DST result | rpoB | Variant | DST result | katG | Variant | DST result | pncA | Variant | DST result | embB | Variant | DST result | rpsL-gidB-rrs-tlyA | |
| NL11-03 | R | S450L | C→T | R | S315T | G→C | R | W119R | T→C | R | Q497R | A→G | R | S |
| NL13-04 | R | S450L | C→T | R | S315T | G→C | S | S | S | R | M306I | G→T | S | S |
| DK01-05 | R | S450L | C→T | R | S315T | G→C | R | A−11G | A→G | R | Q497R | A→G | S | S |
a
RIF, rifampin; INH, isoniazid; PZA, pyrazinamide; EMB, ethambutol; STR, streptomycin; R, resistant; S, susceptible.