Sensitivity of the PUA test by period and grouped serotypes. (A) Sensitivity and 95% confidence intervals for the PUA test by period (i.e., 2001 to 2005, 2006 to 2010, and 2011 to 2015). (B) Sensitivity and 95% confidence intervals for the PUA test by grouped serotypes (i.e., PCV7 serotypes, PCV13 additional serotypes, and non-PCV13 serotypes).