TABLE 1.
Category | Total |
2001–2005 |
2006–2010 |
2011–2015 |
P value |
||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No. of isolates | Sensitivity, % (95% CI) | No. of isolates | Sensitivity, % (95% CI) | No. of isolates | Sensitivity, % (95% CI) | No. of isolates | Sensitivity, % (95% CI) | 2001–2005 vs 2006–2010 | 2006–2010 vs 2011–2015 | 2001–2005 vs 2011–2015 | |
Overall | 1,096 | 72.0 (69.3–74.7) | 195 | 76.4 (70.5–82.4) | 547 | 77.9 (74.4–81.4) | 354 | 60.5 (55.4–65.6) | 0.673 | <0.001 | <0.001 |
Age (yr) | |||||||||||
<65 | 491 | 74.5 (70.7–78.4) | 101 | 80.2 (72.4–88.0) | 252 | 78.2 (73.1–83.3) | 138 | 63.8 (55.8–71.8) | 0.675 | 0.002 | 0.006 |
≥65 | 605 | 69.9 (66.3–73.6) | 94 | 72.3 (63.3–81.4) | 295 | 77.6 (72.9–82.4) | 216 | 58.3 (51.8–64.9) | 0.294 | <0.001 | 0.019 |
Pneumococcal pneumonia | |||||||||||
Proven | 560 | 83.2 (80.1–86.3) | 95 | 83.2 (75.7–90.7) | 282 | 86.5 (82.5–90.5) | 183 | 78.1 (72.1–84.1) | 0.418 | 0.018 | 0.323 |
Probable | 536 | 60.3 (56.2–64.4) | 100 | 70.0 (61.0–79.0) | 265 | 68.7 (63.1–74.3) | 171 | 41.5 (34.1–48.9) | 0.808 | <0.001 | <0.001 |