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. 2018 Jan 24;56(2):e01608-17. doi: 10.1128/JCM.01608-17

TABLE 1.

Reported tools available for diagnostic testing for patients with HHCDs and tool locations closest to the patient care room in 32 U.S. HLIUs

Tool No. (%) available
For HLIU Within patient care room Within isolation unit Within facility Outside facilitya Other
Incubator for bacterial cultureb 30 (94) 0 (0) 8 (27) 19 (63) 2 (7) 1c (3)
Biological safety cabinet 31 (97) 0 (0) 17 (55) 14 (45) 0 (0) 0 (0)
PCR assay 28 (88) 0 (0) 9d (32) 11d (39) 8e (29) 0 (0)
EIA readerf 19 (59) 1 (5) 4 (21) 11 (58) 2 (11) 1c (5)
Microscope 23 (72) 0 (0) 6 (26) 17 (74) 0 (0) 0 (0)
a

Including the jurisdictional PHL (excluding the CDC laboratory for confirmation diagnosis).

b

Including the availability of a standalone incubator for bacterial culture; although this did not include automated blood culture systems, many facilities preferred to incubate blood culture bottles in a standalone incubator for visual observation, with Gram staining and culture performed when necessary.

c

The health system's core laboratory.

d

PCR testing within the isolation unit or facility generally included access to BioFire instrumentation (BioFire, Salt Lake City, UT), including the FDA emergency use authorization-approved FilmArray Biothreat Etest to test for the presumptive presence of Ebola Zaire virus, as well as FDA-approved FilmArray assays including panels for blood culture identification (BCID) and gastrointestinal tract and respiratory tract pathogens.

e

Jurisdictional PHLs utilized real-time PCR assays developed by the CDC and validated in-house to test for pathogens such as Ebola Zaire virus, novel Middle Eastern respiratory syndrome (MERS) coronavirus, and influenza A/H7 virus.

f

Including enzyme immunoassay (EIA) readers for the direct detection of agents such as influenza viruses, group A Streptococcus, HIV, and malaria.