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Confocal laser scanning micrographs showing the effects of CD101 and fluconazole on mature-phase C. albicans biofilms. Top-down three-dimensional views of biofilms exposed to no drug (A), 0.25 μg/ml CD101 (B), 1 μg/ml CD101 (C), 1 μg/ml fluconazole (D), or 4 μg/ml fluconazole (E). Arrows show bulged/broken cells. Thicknesses of Candida biofilms exposed to CD101 (F) or fluconazole (G). *, P value for comparison with untreated control.
