TABLE 3.

Pharmacokinetic parameters of tilorone after i.p. administration to BALB/c mice

Dose (mg/kg)	Sex	t1/2 (h)	Tmax (h)	Cmax (ng/ml)		AUClast (h-ng/ml)		AUCinf (h-ng/ml)	CL/F (ml/h/kg)	V/F (ml/kg)
				Mean	SE	Mean	SE
2	M	15.7	0.083	50.5	5.84	356	39.6	516	87,900	3,870
2	F	18.7	0.083	17.5	3.55	133	9.16	210	257,000	9,510
10	M	20.8	0.25	135	2.33	1099	69.6	1940	155,000	5,160
10	F	18.9	0.25	92.3	7.85	513	74.0	793	343,000	12,600