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. 2018 Jan 23;8:9. doi: 10.3389/fcimb.2018.00009

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Copyright © 2018 Kang, Jin and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular infiltration into the CNS of mice treated with anti-KC antibody and control mice. (A) The proportions of Gr-1⁺CD45⁺ neutrophils in the CNS of TMEV-infected mice treated with anti-KC and control antibodies were assessed using flow cytometry. (B) The numbers of Gr-1⁺CD45⁺ cells in mice treated with anti-KC antibody compared to control mice at early infection (7 dpi), during disease onset (21 dpi), and after the development of disease were assessed. The overall numbers of CD45⁺ cells (C) and CD4⁺ and CD8⁺ T cells (D) in the antibody-treated mice during the period of viral infection are shown. Values given are the means (± SD) of the results from 2 to 3 independent experiments. ^*p < 0.05.