Figure 7.

Humoral responses against A20 lymphoma cells. Anti-A20 lymphoma IgG levels were determined in serum by ELISA at days 12, 22, 36, and 42 p.t.i. for PBS and LVR01x3 groups, and at days 36, 42, and 63 for two cycles of CHOP (CHOPx2) and CHOPx2 + LVR01x3 groups. IgG basal levels were determined in naïve mice at day 0 p.t.i. Data are shown as mean of arbitrary units (A.U.) ± SD (n = 5). At days 36 and 42 p.t.i. LVR01x3 and CHOPx2 + LVR01x3 developed a significantly higher anti-A20 IgG antibody response compared with PBS and CHOPx2 groups; at day 63 p.t.i. significant differences between CHOPx2 and CHOPx2 + LVR01x3 groups still remained. Significant differences are shown with P value (analysis of variance, Student’s t-test).