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. 2018 Jan 23;5:1. doi: 10.3389/fmed.2018.00001

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Copyright © 2018 He, Guo and Goyal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Membrane hyperpolarization to nitrergic agonist, diethylenetriamine nitric oxide adduct (DNO). Panel (A) shows actual examples and panel (B) shows cumulative data on the amplitudes of the nitrergic inhibitory junction potential. Note that hyperpolarization to DNO in hyperglycemic NOD (H-NOD) was similar to wild-type (WT) control.