Table 2.
Median value (minimum; maximum) of selected blood parameters of dogs with Ehrlichia canis and number of dogs below (↓) or above (↑) the normal range
| Parameter (Normal Range) | PCV (37.5–55.0%) | Lymphocytes (1–4.8 × 109) | Platelets (200–500 × 109) | Globulin (2.3–5.2 g/dL) |
|---|---|---|---|---|
| Doxycycline treated (N = 5) | ||||
| Pretreatment |
40 (31; 44) 1 ↓ |
2.8 (0.9; 7.0) 1 ↓; 1 ↑ |
86 (55; 225) 4 ↓ |
7.1 (3.8; 7.8) 4 ↑ |
| Day 28 of treatment |
40b (38; 45) – |
2.6 (1.2; 6.4) 1 ↑ |
175 (71; 285) 4 ↓ |
Not determined |
| 7 days post‐treatment |
44 (38; 45) – |
2.8 (0.7; 4.4) 1 ↓ |
225c (90; 268) 2 ↓ |
4.7 (2.5; 6) 1 ↑ |
| % changec | 0 (−5; 42) | −0.7 (−38; 84) | 27 (4.7; 362) | −34.2 (−15.5; −39.7) |
| Minocycline treated (N = 5) | ||||
| Pretreatment |
34 (28; 52) 4 ↓ |
2.1 (1.1; 4.9) 1 ↑ |
141 (104; 261) 4 ↓ |
5.8 (2.6; 6.1) 3 ↑ |
| Day 28 of treatment |
40 (34; 53) 2 ↓ |
1.8 (0.2; 4.8) 1 ↓ |
298 (144; 337) 2 ↓ |
Not determined |
| 7 days post‐treatment |
40 (30; 50) 1 ↓ |
2.0 (1.2; 3.1) – |
279 (152; 323) 2 ↓ |
3.7b (2.4; 5.3) 1 ↑ |
| % changea | 14.3 (−4; 24) | 12.3 (−52; 36) | 61.5 (6.9; 211) | −21.2 b(−7.7; −43.1) |
a
Percent change pre‐ to 7 days post‐treatment calculated for each dog and then averaged for the treatment group. A negative number indicates a decrease in the value.
b
Data for one dog missing.
c
Platelet reading was 1 for one dog; a follow‐up reading was 244. Due to the discrepancy, this dog is omitted from the analysis on this day.