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. 2017 Nov 9;32(1):361–369. doi: 10.1111/jvim.14860

Figure 2.

Figure 2

Total STAT3 has an increased nuclear expression in canine DLBCL. Immunohistochemistry was conducted to evaluate nuclear versus cytoplasmic expression of STAT3 (A‐C) and p‐STAT3 (D‐F) in canine normal lymph nodes (A, D), canine reactive lymph nodes (B, E), and canine DLBCL (C, F). (G) Mean (±SD) percentage of cytoplasmic staining versus both cytoplasmic and nuclear staining in STAT3 immunolabelled cells. Red arrow head: cytoplasmic staining, black arrow: nuclear staining, black arrow head: both cytoplasmic and nuclear staining. Normal lymph nodes (n = 10), reactive lymph nodes (n = 10) and DLBCL (n = 42) (***P < 0.0001).