Table 6.

Univariate and multivariate analysis of factors potentially associated with MHT ≥ 10%

Variables	Frequency of MHT ≥ 10%	Univariate analysis	Multivariate analysis
FLR <50% vs > 50%	92.4 vs 68.4%	p = 0.0203	p = 0.0023
HILD <88Gy vs ≥ 88Gy	65.7% vs 92.2	p = 0.0081	p = 0.0029
TD ≥205Gy and TV ≥ 100cm 3 vs TD <205Gy or TV < 100 cm3	81.8 vs 75.8%	ns	–
HILD ≥88Gy or TD ≥205Gy for TV ≥ 100cm 3 vs HILD <88Gy and TD <205Gy or TV < 100 cm3	83.9 vs 54.5%	p = 0.0265	not tested*
Child A5 vs A6 + B7	89.6 vs 40.0%	p = 0.0001	p < 0.0001
PVT present vs absent	81.8 vs 78.9%	ns	–
Hypersplenism present vs absent	71.4 vs 80.7%	ns	–
Response vs no response	81.4 vs 33.3%	ns	–
Liver toxicity vs no liver toxicity	75.0 vs 79.7%	ns	–
First line vs ≥ second line	72.9 vs 92.9%	ns, but trends (p = 0.0706)	–

The mixed variable HILD ≥88Gy or TD _{≥ 205Gy for TV ≥ 100cm} ³ was not tested in multivariate analysis as this variable depends on the variables HILD ≥88Gy and TD _{≥ 205Gy for TV ≥ 100cm} ³