Table 3.

Efficiency of ⁶⁸Ga-PSMA PET/CT in patients with biochemical relapse (low rising PSA) – status October 2017

AUTHORS	DESIGN	TOTAL number	PSA 0.0–0.1	PSA 0.1–0.2	PSA 0.2–0.3	PSA 0.3–0.5	PSA 0.5–0.8	PSA 0.8 < 1	PSA 1–2	PSA > 2	PET/CT SCANNER	IMAGE AQUISITION
van Leeuwen et al. [53]	Prosp	n = 300	n = 13	n = 22	n = 17	n = 11	n = 7				Ingenuity TOF, Philips	45 min
			8%	23%	58%	36%	57%
Afshar-Oromieh et al. [54] Afshar-Oromieh et al. [55]	Retrosp Retrosp	n = 319 (83%)* n = 801/ 1007 (79.5%)*	n = 8/17		n = 5/10		n = 14/24		n = 28/39		Biograph, Siemens	60 min
			47.10%		50%		58.30%		71.80%
			n = 32/69		n = 50/108		n = 87/119		n = 132/166	n = 467/509
			46%		46%		73%		80%	91.75%
Eiber et al. [56] Maurer et al. [75] Einspieler et al. [57]	Retrosp Retrosp Retrosp	n = 248 (90%)* n = 332 107/118 (90.7%)*			n = 11/19		n = 24/33		n = 67/72	n = 120/124	Biograph, Siemens	60 min
					57.89%		72.73%		93.06%	96.77%
					n = 13/23		n = 25/35		n = 67/71	n = 122/127
					56.5%		71.4%		94.4%	96.1%
										n = 107/118
										(90.7%)
Verburg et al. [51]	Retrosp	n = 155 (89%)*	n = 12/27						n = 15/19	n = 97/109	GEMINI TF16, Philips	60 min
			44%						79%	89%
Morigi et al. [85]	Prosp	n = 37/38	n = 8/16				n = 10/14			n = 7/8	Ingenuity TOF, Philips	45 min
			50%				71%			88%
Kabasakal [58]	Retrosp	n = 29/50 (58%)*	n = 4		n = 11					n = 14	Biograph, Siemens	45–60 min
			33%		50%					87.5%
Ceci et al. [50]	Retrosp	n = 52/70 (74.2%)*	n = 21				n = 49				Discovery, GE	8 min, 60 min, (120 min)
			47.60%				85.70%
Sachpekidis et al. [59]	Retrosp	n = 22/31 (71%)*	n = 4/11						n = 15/20		Biograph, Siemens	Dynamic for 60 min (pelvis), WB at 80–90 min p.i.
			36.36%						75%
Albisinni et al. [62]	Retrosp	n = 98/131 (75%)	45%						83%		GE Discovery 690	60 min

*Overall detection rate