Table 1.
Cells (% of GFP+PD-L1high by flow cytometry) | CMT167 orthotopic (n = 4 pools of 2 mice) | CMT167 subcutaneous (n = 7 tumors) | LLC orthotopic (n = 4 pools of 2 mice) |
---|---|---|---|
Alveolar macrophages | 59.4 ± 4.98 | N.D. | 46.3 ± 4.40 |
Interstitial and monocyte-derived recruited macrophages | 24.2 ± 2.03 | 67.66 ± 2.29 | 45.6 ± 4.33 |
Dendritic cells | 4.0 ± 1.46 | 1.8 ± 1.60 | 1.5 ± 1.43 |
CD11b+Ly6G+ myeloid cells | N.D. | 28.66 ± 1.60 | 2.5 ± 1.37 |
Endothelial cells | 4.1 ± 1.44 | 1.8 ± 1.29 | 0.7 ± 0.66 |
Total PD-L1high (% of GFP+ cells) | 16.88 ± 0.84 | 8.05 ± 1.90 | 9.53 ± 0.95 |
Statistically significant differences by ANOVA compared to CMT167 orthotopic tumors are shown in bold. N.D. = not detected