Table 2.
Full Group Associationsa
| Model | Covariate | Unit/Reference | vs. | Covariate OR | Az |
|---|---|---|---|---|---|
| LR(A) = Censored Group | Age | 8.4265 | NA | 0.61 (0.43, 0.87) | 0.630 |
| LR(G) = Censored Group | Sex | Female | Male | 0.36 (0.18, 0.69) | 0.627 |
| LR(T) = Censored Group | Adjuvant treatment | No | Yes | 0.50 (0.19, 1.31) | 0.537 |
| LR(Gr) = Censored Group | Grade | 1.0000 | NA | 0.74 (0.45, 1.20) | 0.549 |
| LR(S1) = Censored Group | Stage I disease | A | B | 0.59 (0.30, 1.16) | 0.558 |
| LR(KP) = Censored Group | KP | 5.1212 | NA | 1.03 (0.75, 1.41) | 0.479 |
| LR(KS) = Censored Group | KS | 22.7532 | NA | 0.95 (0.68, 1.32) | 0.530 |
| LR(PI) = Censored Group | PI | 0.6120 | NA | 0.90 (0.65, 1.25) | 0.527 |
| LR(PP) = Censored Group | PP | 17.8968 | NA | 1.08 (0.79, 1.47) | 0.540 |
| LR(PS) = Censored Group | PS | 76.7112 | NA | 0.98 (0.71, 1.34) | 0.498 |
| LR(A,S) = Censored Group | Age | 8.4265 | NA | 0.64 (0.44, 0.91) | 0.683 |
| Sex | Female | Male | 0.39 (0.20, 0.75) |
The DNA expression measures for KU86 and PARP for the intensity, proportions and total score are A, KI, KP, KS and PI, PP, and PS, respectively.
This model included age (A), sex (S), adjuvant treatment (T) tumor grade (Gr), stage I subgroup (S1), Histologic sub type (H) restricted to adenocarcinoma (AC) and SCC, tumor location (loc), and DNA expression measures. The step-forward selection procedure was used to build a model to predict the censored group (favorable group). Only sex and the 2 histologic subtype variables were significant (univariate models). The odds ratios (ORs) with 95% confidence intervals and area underthe receiver operating characteristic curve (Az) are provided for the various arrangements. We use the functional notation LR(x, y) = censored group to indicate the variables (ie, the respective covariates listed in the table) within the LR model used to predict the censored group. Entries that are not applicable are marked NA.