Table 3. Overlap between age co-expressed genes and GenAge genes.
Tissue |
#Age co-expressed genes |
#GenAge genes |
Background Genes |
#Overlap genes |
Ratio* | P-value# |
---|---|---|---|---|---|---|
adipose | 2563 | 305 | 16516 | 155 | 50.82 | 5.21E-51 |
Artery | 821 | 305 | 16096 | 56 | 18.36 | 4.45E-18 |
heart | 2490 | 305 | 15721 | 137 | 44.92 | 8.02E-37 |
lung | 1157 | 305 | 16853 | 80 | 26.23 | 3.68E-27 |
muscle | 2025 | 305 | 15928 | 117 | 38.36 | 3.60E-33 |
nerve | 769 | 305 | 16557 | 56 | 18.36 | 3.68E-20 |
skin | 774 | 305 | 16733 | 47 | 15.41 | 5.91E-14 |
thyroid | 1260 | 305 | 16737 | 69 | 22.62 | 1.09E-17 |
whole blood | 1035 | 305 | 16025 | 69 | 22.62 | 1.09E-17 |
*Ratio is calculated as the number of overlap genes divided by that of the GenAge genes. #P-value is calculated by the one-sided Fisher’s exact test.