Figure 5. CCAR expression in tissues from cervical cancer patients is negatively correlated with that of IL-8.

(A) Expression of CCAR2 and IL-8 protein in tumor tissues from cervical cancer patients was examined by IHC (n = 47). The immunostaining score is described in the Methods. The association between CCAR2 and IL-8 expression was determined using Pearson’s chi square (χ²) test. (B, C) Information regarding expression of CCAR2 and IL-8 mRNA in tumor tissues from cervical cancer patients was downloaded from the GEO (GSE27469) (n = 82) (B) and TCGA (n = 304) (C) databases. Pearson correlation analysis was used to quantify the relationship between CCAR2 and IL-8. r, Pearson’s correlation coefficient; P, P-value.