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. 2017 Dec 19;9(1):1156–1168. doi: 10.18632/oncotarget.23452

Figure 7. Expression of active form of Notch1 (NICD1) in NSCLC tissues and cells.

Figure 7

(A), (B) Overexpression of lncRNA-LET (P-Lenti-IncRNA-LET) reduced NICD1 expression in H292 cells. (C), (D) Knockdown of lncRNA-LET (sh-IncRNA-LET) increased NICD1 expression in H1975 cells. (E), (F) Expression of NICD1 protein from NSCLC tissues with low (n=3) or high (n=3) LncRNA-LET expression levels. Relative NICD1 expressions from densitometry analysis of the blots after normalization to β-actin represent the mean ± S.D. from three independent experiments (B, D), and from ten NSCLC lung tissue samples (F). **P<0.01.